Anti-Viral Therapeutics Market Size & Share Analysis - Growth Trends & Forecasts (2025 - 2030)

The Anti-Viral Therapeutics Market Report is Segmented by Virus Type (HIV & AIDS, Hepatitis B, Hepatitis C, and More), Drug Class (Reverse Transcriptase Inhibitors, Protease Inhibitors, Polymerase/Nucleoside Analog Inhibitors, and More), Route of Administration (Oral, Injectable, and More), and Geography (North America, Europe, and More). The Market Forecasts are Provided in Terms of Value (USD).

Anti-Viral Therapeutics Market Size and Share

Anti Viral Therapeutics Market Summary
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Compare market size and growth of Anti-Viral Therapeutics Market with other markets in Healthcare Industry

Anti-Viral Therapeutics Market Analysis by Mordor Intelligence

The Anti-Viral Therapeutics market size is USD 56.71 billion in 2025 and is forecast to reach USD 62.80 billion by 2030 at a 2.06% CAGR, highlighting a stable but opportunity-rich arena where legacy small molecules meet high-value delivery innovations. Long-acting formulations, AI-guided lead discovery, and government-backed broad-spectrum programs headline the current investment focus, while patent expiries on first-generation antivirals temper headline growth. Therapeutic developers are prioritizing real-world evidence packages to secure favorable reimbursement as price-control rules tighten in major economies. Competitive intensity remains moderate because scale players still dominate global distribution, yet differentiated biotech pipelines are attracting premium partnerships. The Anti-Viral Therapeutics market is also navigating supply-chain hardening, with cold-chain capacity expansions enabling wider access to biologics and long-acting injectables.

Key Report Takeaways

By virus type, influenza antivirals led with 46.29% revenue share in 2024; COVID-19/SARS-CoV-2 therapeutics is projected to expand at a 3.78% CAGR through 2030.

By drug class, reverse transcriptase inhibitors accounted for 33.94% of the Anti-Viral Therapeutics market share in 2024, whereas capsid inhibitors are forecast to grow at a 3.91% CAGR to 2030.

By route of administration, oral therapies commanded 64.28% share of the Anti-Viral Therapeutics market size in 2024, while topical formulations are advancing at 4.05% CAGR through 2030.

By geography, North America held 34.91% of 2024 revenue and Asia-Pacific is on track for the fastest 4.19% CAGR between 2025-2030.

Segment Analysis

By Virus Type: Influenza Dominance Faces Emerging Threats

Influenza antivirals delivered USD 26.2 billion in 2024, equal to 46.29% of the Anti-Viral Therapeutics market size, underscoring entrenched seasonal demand and clinical familiarity. Steady pipeline progress toward polymerase acidic (PA) and polymerase basic (PB2) inhibitors broadens therapeutic options and may counter neuraminidase resistance. Meanwhile, COVID-19/SARS-CoV-2 treatments, though originating from pandemic urgency, now post a 3.78% CAGR through 2030 as post-exposure prophylaxis gains favor, especially among immunocompromised cohorts. Mature hepatitis B and C segments plateau because cure or functional-cure regimens shorten treatment durations, yet remain sizeable given disease burden in Asia and Africa. Herpes therapies are benefiting from micro-needle patches and in-situ gel formulations that promise superior lesion control. RSV and CMV programs leverage monoclonal antibodies and small-molecule fusion inhibitors, with pediatric indications offering growth headroom.

The Anti-Viral Therapeutics market shifts from single-pathogen strategies to host-targeted or broad-spectrum agents poised for pandemic readiness. Such programs attract non-dilutive public funding and can bypass narrow epidemiological peaks. CMV assets still address niche transplant populations, leading to premium pricing but limited volumes. Future competitive landscapes will hinge on rapid outbreak response capacity and cross-family efficacy, redrawing the virus-type hierarchy over the forecast horizon.

Anti-Viral Therapeutics Market: Market Share by Virus Type
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Note: Segment shares of all individual segments available upon report purchase

By Drug Class: Traditional Mechanisms Meet Novel Targets

Reverse transcriptase inhibitors retained a 33.94% Anti-Viral Therapeutics market share in 2024, propelled by backbone status in HIV and hepatitis B therapy. Incremental chemical tweaks improve resistance barriers and renal profiles, sustaining relevance against generic incursion. Capsid inhibitors, fronted by lenacapavir, show a category-leading 3.91% CAGR and are reshaping dose-frequency expectations through twice-yearly administration. Protease inhibitors remain vital in acute COVID-19 management, while polymerase/nucleoside analogs hold cross-viral credibility but seek differentiation via inhalable and pediatric formulations.

RNAi and antisense modalities press into late-phase trials, yet face delivery challenges that temper near-term commercial impact. Broad-spectrum small molecules court government stockpile contracts, providing a hedge against unpredictable outbreaks. Companies with balanced portfolios across these mechanistic classes are best placed to ride out resistance cycles and pricing volatility. Over the next five years, the Anti-Viral Therapeutics market size attached to capsid-based and host-factor inhibitors could double as clinical validation and manufacturing scale converge.

By Route of Administration: Oral Convenience Drives Market Share

Oral products captured 64.28% of global revenue in 2024, equivalent to USD 36.5 billion of the Anti-Viral Therapeutics market size, thanks to outpatient feasibility and pandemic-era telehealth prescribing. Reformulations that decouple absorption from food intake are further widening candidacy. Injectable formulations, particularly long-acting intramuscular agents, defend adherence-sensitive HIV and hepatitis segments, with device innovations reducing injection-site discomfort. Topical antivirals grow fastest at 4.05% CAGR, supported by thermoresponsive gels and nanoparticle creams that localize high drug loads for herpes or respiratory mucosal infections.

Emergent inhalation and nasal routes aim to deliver prophylaxis directly to respiratory epithelium, offering rapid onset for pandemic response toolkits. Route selection is increasingly patient-segmented: chronic suppressive therapy looks to depot injectables; acute, self-limiting infections favor fast-acting orals; localized disease leans topical. This diversity supports parallel growth tracks that sustain the Anti-Viral Therapeutics market beyond one-size‐fits-all formularies.

Anti-Viral Therapeutics Market: Market Share by Route of Administration
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Note: Segment shares of all individual segments available upon report purchase

Geography Analysis

North America represented 34.91% of 2024 sales, buoyed by the FDA’s streamlined designations and deep payer wallets that reimburse premium antivirals. US-centric R&D hubs fast-track first-in-class assets, and integrated specialty-pharmacy logistics ensure prompt nationwide distribution. However, Medicare’s drug-price negotiations are set to pressure free-on-board prices, nudging firms toward value-based contracts that hinge on real-world virologic outcomes.

Asia-Pacific posts the fastest 4.19% CAGR as China, India, and Southeast Asia invest heavily in domestic pharmaceutical capacity and universal insurance schemes. China’s 2024 tally of 228 novel drug approvals signals regulator intent to match Western review speeds, drawing multinationals into local co-development partnerships. India leverages cost-optimized production to supply regional demand, and Japanese aging demographics support sustained antivirals usage for reactivated herpes zoster and RSV. Simultaneously, improving cold-chain frameworks unlock broader biologics access, further expanding the regional Anti-Viral Therapeutics market.

Europe maintains steady value but negotiates harder on price, using health technology assessments to enforce cost-effectiveness thresholds. EMA’s centralized procedure remains attractive for simultaneous bloc entry, yet post-Brexit dual filings add complexity. Southern and Eastern European nations, supported by EU healthcare restructuring funds, offer incremental volume upside as vaccine and antiviral awareness climbs. Collectively, geographic diversification spreads revenue risk but raises compliance costs, making global regulatory mastery a core competence for sector leaders.

Anti-Viral Therapeutics Market CAGR (%), Growth Rate by Region
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Competitive Landscape

The Anti-Viral Therapeutics market is moderately concentrated, with the top five players controlling significant but not overwhelming share; Gilead, GSK-ViiV, and Merck headline the incumbents. Their edge lies in global commercialization machinery and multi-mechanism portfolios that cushion against single-asset setbacks. Partnership deals have intensified: Merck pairs its islatravir pipeline with Gilead’s lenacapavir to craft a once-monthly oral prevention regimen, while Pfizer’s USD 525 million buyout of ReViral fortifies its RSV ambitions. Such moves blend big-pharma balance sheets with biotech agility, accelerating late-stage progressions and filling mechanism gaps.

Biotech challengers wield AI discovery, RNA-based mechanisms, and novel delivery devices to carve niches. Exscientia’s machine-learning pipeline has already attracted Gates Foundation backing, underscoring the growing synergy between philanthropy and commercial R&D. Meanwhile, digital-health adjuncts—adherence apps, home diagnostics—are becoming standard accessories in new product launches to satisfy payer evidence demands. In manufacturing, leaders are fortifying supply chains with dual-source API contracts and regional fill-finish sites, lessons hard-learned from pandemic disruptions.

Future competitive advantage will revolve around resistance-monitoring ecosystems, cost-effective long-acting formulations, and ability to navigate multi-jurisdiction pricing audits. Companies failing to demonstrate clear real-world value risk formulary exclusion despite regulatory approvals, especially in Europe and an increasingly cost-conscious United States.

Anti-Viral Therapeutics Industry Leaders

  1. AbbVie Inc.

  2. Bristol-Myers Squibb Company

  3. Gilead Sciences Inc.

  4. F. Hoffman-La Roche Ltd

  5. Cipla Inc.

  6. *Disclaimer: Major Players sorted in no particular order
Anti Viral Therapeutics Market Concentration
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Recent Industry Developments

  • March 2025: Shionogi announced Phase 3 SCORPIO-PEP results showing a 67% COVID-19 risk reduction from ensitrelvir post-exposure prophylaxis. FDA granted Fast Track status
  • March 2025: Gilead and GSK-ViiV advanced once-yearly lenacapavir and VH499/VH184 HIV prevention programs into Phase III after favorable Phase I data

Table of Contents for Anti-Viral Therapeutics Industry Report

1. Introduction

  • 1.1 Study Assumptions & Market Definition
  • 1.2 Scope of the Study

2. Research Methodology

3. Executive Summary

4. Market Landscape

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Expanding long-acting injectable pipelines
    • 4.2.2 Surge in HIV combination-therapy adoption
    • 4.2.3 COVID-19-driven antiviral R&D spill-over
    • 4.2.4 AI-enabled nucleos(t)ide analog design
    • 4.2.5 Public-sector funding for broad-spectrum agents
    • 4.2.6 mRNA platforms pivoting to antivirals
  • 4.3 Market Restraints
    • 4.3.1 Rising antiviral-resistance mutations
    • 4.3.2 Price-control & reimbursement headwinds
    • 4.3.3 Biosafety-grade manufacturing bottlenecks
    • 4.3.4 Cold-chain gaps in low-income regions
  • 4.4 Value / Supply-Chain Analysis
  • 4.5 Regulatory Landscape
  • 4.6 Technological Outlook
  • 4.7 Porter’s Five Forces
    • 4.7.1 Bargaining Power of Buyers
    • 4.7.2 Bargaining Power of Suppliers
    • 4.7.3 Threat of New Entrants
    • 4.7.4 Threat of Substitutes
    • 4.7.5 Industry Rivalry

5. Market Size & Growth Forecasts (Value, USD)

  • 5.1 By Virus Type
    • 5.1.1 HIV & AIDS
    • 5.1.2 Hepatitis B
    • 5.1.3 Hepatitis C
    • 5.1.4 Influenza
    • 5.1.5 Herpes (HSV)
    • 5.1.6 Respiratory Syncytial Virus (RSV)
    • 5.1.7 Cytomegalovirus (CMV)
    • 5.1.8 Other & Emerging Viruses
  • 5.2 By Drug Class / Mechanism
    • 5.2.1 Reverse Transcriptase Inhibitors (NRTI/NNRTI)
    • 5.2.2 Protease Inhibitors
    • 5.2.3 Polymerase / Nucleoside Analog Inhibitors
    • 5.2.4 RNAi & Antisense Therapeutics
    • 5.2.5 Broad-spectrum Small-molecule Antivirals
    • 5.2.6 Capsid Inhibitors
    • 5.2.7 Others
  • 5.3 By Route of Administration
    • 5.3.1 Oral
    • 5.3.2 Injectable (incl. Long-Acting)
    • 5.3.3 Topical
    • 5.3.4 Others
  • 5.4 By Region
    • 5.4.1 North America
    • 5.4.1.1 United States
    • 5.4.1.2 Canada
    • 5.4.1.3 Mexico
    • 5.4.2 Europe
    • 5.4.2.1 Germany
    • 5.4.2.2 United Kingdom
    • 5.4.2.3 France
    • 5.4.2.4 Italy
    • 5.4.2.5 Spain
    • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
    • 5.4.3.1 China
    • 5.4.3.2 India
    • 5.4.3.3 Japan
    • 5.4.3.4 South Korea
    • 5.4.3.5 Australia
    • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 South America
    • 5.4.4.1 Brazil
    • 5.4.4.2 Argentina
    • 5.4.4.3 Rest of South America
    • 5.4.5 Middle East and Africa
    • 5.4.5.1 GCC
    • 5.4.5.2 South Africa
    • 5.4.5.3 Rest of Middle East and Africa

6. Competitive Landscape

  • 6.1 Market Concentration
  • 6.2 Market Share Analysis
  • 6.3 Company Profiles (includes Global level Overview, Market level overview, Core Segments, Financials as available, Strategic Information, Market Rank/Share for key companies, Products & Services, and Recent Developments)
    • 6.3.1 Gilead Sciences Inc.
    • 6.3.2 GlaxoSmithKline plc (ViiV Healthcare)
    • 6.3.3 Merck & Co., Inc.
    • 6.3.4 F. Hoffmann-La Roche AG
    • 6.3.5 AbbVie Inc.
    • 6.3.6 Johnson & Johnson (Janssen)
    • 6.3.7 Bristol Myers Squibb Co.
    • 6.3.8 Pfizer Inc.
    • 6.3.9 Novartis AG
    • 6.3.10 AstraZeneca plc
    • 6.3.11 Cipla Ltd.
    • 6.3.12 Dr. Reddy’s Laboratories
    • 6.3.13 Aurobindo Pharma Ltd.
    • 6.3.14 Lupin Ltd.
    • 6.3.15 Sun Pharmaceutical Inds.
    • 6.3.16 Shionogi & Co., Ltd.
    • 6.3.17 Takeda Pharmaceutical Co.
    • 6.3.18 Vir Biotechnology, Inc.
    • 6.3.19 Regeneron Pharmaceuticals
    • 6.3.20 Eli Lilly and Company

7. Market Opportunities & Future Outlook

  • 7.1 White-space & Unmet-need Assessment
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Global Anti-Viral Therapeutics Market Report Scope

Anti-viral drugs are a class of medication used for treating viral infections. While a broad-spectrum antiviral is effective against many viruses, most antivirals target specific viruses. 

Anti-viral Therapeutics Market is Segmented by Drug Type (Herpes Anti-viral Drugs, Hepatitis Anti-viral Drugs, HIV Anti-viral Drugs, Influenza Anti-viral Drugs, and Other Anti-viral Drugs), Distribution Channel (Hospital Pharmacy, Independent Pharmacy, and Drug Store, Online Pharmacy), and Geography (North America (United States, Canada, and Mexico), Europe ) Germany, United Kingdom, France, Italy, Spain, and Rest of Europe), Asia-Pacific (China, Japan, India, Australia, South Korea, and Rest of Asia-Pacific), Middle East and Africa (GCC, South Africa, and the Rest of Middle East and Africa), and South America Brazil, Argentina, and Rest of South America)). The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers value (in USD billion) for the above segments.

By Virus Type HIV & AIDS
Hepatitis B
Hepatitis C
Influenza
Herpes (HSV)
Respiratory Syncytial Virus (RSV)
Cytomegalovirus (CMV)
Other & Emerging Viruses
By Drug Class / Mechanism Reverse Transcriptase Inhibitors (NRTI/NNRTI)
Protease Inhibitors
Polymerase / Nucleoside Analog Inhibitors
RNAi & Antisense Therapeutics
Broad-spectrum Small-molecule Antivirals
Capsid Inhibitors
Others
By Route of Administration Oral
Injectable (incl. Long-Acting)
Topical
Others
By Region North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
India
Japan
South Korea
Australia
Rest of Asia-Pacific
South America Brazil
Argentina
Rest of South America
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
By Virus Type
HIV & AIDS
Hepatitis B
Hepatitis C
Influenza
Herpes (HSV)
Respiratory Syncytial Virus (RSV)
Cytomegalovirus (CMV)
Other & Emerging Viruses
By Drug Class / Mechanism
Reverse Transcriptase Inhibitors (NRTI/NNRTI)
Protease Inhibitors
Polymerase / Nucleoside Analog Inhibitors
RNAi & Antisense Therapeutics
Broad-spectrum Small-molecule Antivirals
Capsid Inhibitors
Others
By Route of Administration
Oral
Injectable (incl. Long-Acting)
Topical
Others
By Region
North America United States
Canada
Mexico
Europe Germany
United Kingdom
France
Italy
Spain
Rest of Europe
Asia-Pacific China
India
Japan
South Korea
Australia
Rest of Asia-Pacific
South America Brazil
Argentina
Rest of South America
Middle East and Africa GCC
South Africa
Rest of Middle East and Africa
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Key Questions Answered in the Report

1. What is the current Anti-Viral Therapeutics market size and growth outlook?

The Anti-Viral Therapeutics market size is USD 56.71 billion in 2025 and is projected to reach USD 62.80 billion by 2030 at a 2.06% CAGR.

2. Which virus segment leads the Anti-Viral Therapeutics market?

Influenza antivirals hold the lead with a 46.29% revenue share in 2024.

3. Which region is growing fastest for antiviral sales?

Asia-Pacific shows the highest regional CAGR at 4.19% through 2030, driven by expanded healthcare access and local manufacturing scale-up.

4. What drug class is expanding quickest within the market?

Capsid inhibitors post the fastest 3.91% CAGR thanks to long-acting products like lenacapavir.

Page last updated on: July 21, 2025

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